Contents

Research Areas

Magnetic Nanoparticles​ (MNPs)
Synthesis and functionalization of magnetic nanoparticles; their use in imaging, targeted drug delivery, and hyperthermia applications.
Functional Material Design

Surface modification, characterization, and biological testing of biocompatible and multifunctional nanomaterials.

Cancer Treatment and Biomedical Applications

Innovative approaches to cancer treatment using magnetic hyperthermia, gene therapy, and innovative nanoparticle systems.

Molecular Mechanisms

Biochemical analysis of cellular stress responses, oxidative stress, and signaling pathways.

Papers

After 2025

  1. Aksoy, H. R., Solak, K., MAVI, A., & Nadaroglu, H. Magnetic Hyperthermic and Anticancer Properties of Hydrothermally Synthesized Magnetic Nanoparticles Using Gypsophila. Journal of Magnetism and Magnetic Materials. 636, 173639 .https://doi.org/10.1016/j.jmmm.2025.173639

  2. Solak, K., Mavi, A., Taghizadehghalehjoughi, A., Yildirim, S., Genç, S., & Hacımüftüoğlu, A. (2025). Enhanced antitumor effects of interferon-stimulating DNA and magnetic hyperthermia in a breast cancer rat model. Journal of Drug Delivery Science and Technology, 110, 103933. https://doi.org/10.1016/j.jddst.2025.103933

  3. Dagci, I., Arslan, S. Y., Solak, K., Acar, M., Ünver, Y., & Mavi, A. (2025). Methanol-free protein expression in Komagataella phaffii with magnetic or non-magnetic heating. Microbial Biotechnology, 18(6), 1–13. https://doi.org/10.1111/1751-7915.13850

  4. Solak, K., Arslan, S. Y., Acar, M., Turhan, F., Ünver, Y., & Mavi, A. (2025). Combination of magnetic hyperthermia and gene therapy for breast cancer. Apoptosis, 30(1–2), 99–116. https://doi.org/10.1007/s10495-024-01890-2

  5. Solak, K., Atiş, M., Kasapoğlu, A. E., Karaman, A., & Mavi, A. (2025). Metal nanoparticles for simultaneous use in AC magnetic field hyperthermia and magnetic resonance imaging. Journal of Biomedical Materials Research – Part A, 113(1), 145–160. https://doi.org/10.1002/jbm.a.37425

Before 2025
  1. Dagci, I., Solak, K., Oncer, N., Yildiz Arslan, S., Unver, Y., Yilmaz, M., et al. (2024). Machine learning-assisted SERS reveals the biochemical signature of enhanced protein secretion from surface-modified magnetic nanoparticles. ACS Applied Materials & Interfaces, 16(51), 70392–70406. https://doi.org/10.1021/acsami.4c20000
  2. Güney, B. N., Kızıloğlu, H. T., Solak, K., Ulusoy, D., & Kara, A. (2024). Investigation of the Effects of Metformin and Ifosfamide Applications on Cell Proliferation and Apoptosis in Hepatocellular Carcinoma Cells. Eurasian Journal of Molecular and Biochemical Sciences, 3(1), 17-24.
  3. Firat, C., Öztürk, A., Dağcı, İ., Ünver, Y., & Solak, K. (2024). NanoScript: A Novel Tool for Gene Regulation Based on Nanoparticles with Benefits and Drawbacks. Eurasian Journal of Molecular and Biochemical Sciences, 3(1), 30-36.
  4. Sancaktutan, Ş., İspahi, B., Arslan, Ş. Y., Solak, K., & Ünver, Y. (2024). Magnetofection: A Magical Technique for Effective Gene Transfer Using Magnetic Nanoparticles. Eurasian Journal of Molecular and Biochemical Sciences, 3(1), 25-29.
  5. Kalakenger, S., Arslan, S. Y., Turhan, F., Acar, M., Solak, K., Mavi, A., et al. (2024). Heterologous expression of codon-optimized azurin transferred by magnetofection method in MCF-10A cells. Molecular Biotechnology, 66(6), 1434–1445. https://doi.org/10.1007/s12033-024-00800-0
  6. Gul, R., Muhammad, N., Sirajuddin, M., Noor, A., Tumanov, N., Wouters, J., et al. (2024). Design, physicochemical confirmation, single crystal structures as well as exploration of antibacterial and anticancer potential of organotin(IV) carboxylates. Journal of Molecular Structure, 1300, 131–145. https://doi.org/10.1016/j.molstruc.2024.131045
  7. Celik, S., Solak, K., & Mavi, A. (2023). Sulfanilamide modified magnetic nanoparticles for purification of carbonic anhydrase from bovine blood. Applied Biochemistry and Biotechnology, 195(6), 3900–3913. https://doi.org/10.1007/s12010-023-04325-x
  8. Acar, M., Solak, K., Yildiz, S., Ünver, Y., & Mavi, A. (2022). Comparative heating efficiency and cytotoxicity of magnetic silica nanoparticles for magnetic hyperthermia treatment on human breast cancer cells. 3 Biotech, 12(11), 421. https://doi.org/10.1007/s13205-022-03315-1
  9. Kim, H., Solak, K., Han, Y., Cho, Y., Koo, K., Kim, C., et al. (2022). Electrically controlled mRNA delivery using a polypyrrole-graphene oxide hybrid film to promote osteogenic differentiation of human mesenchymal stem cells. Nano Research, 15(10), 9253–9263. https://doi.org/10.1007/s12274-022-4545-9
  10. Muhammad, N., Ahmad, M., Sirajuddin, M., Ali, Z., Tumanov, N., Wouters, J., et al. (2022). Synthesis, characterization, biological activity and molecular docking studies of novel organotin(IV) carboxylates. Frontiers in Pharmacology, 13, 987654. https://doi.org/10.3389/fphar.2022.987654
  11. Yildiz, S., Solak, K., Acar, M., Mavi, A., & Ünver, Y. (2021). Magnetic nanoparticle mediated-gene delivery for simpler and more effective transformation of Pichia pastoris. Nanoscale Advances, 3, 4482–4491. https://doi.org/10.1039/D1NA00354H
  12. Solak, K., Mavi, A., & Yilmaz, B. (2021). Disulfiram-loaded functionalized magnetic nanoparticles combined with copper and sodium nitroprusside in breast cancer cells. Materials Science & Engineering C-Materials for Biological Applications, 119, 111700. https://doi.org/10.1016/j.msec.2020.111700
  13. Chafik, A., Essamadi, A., Çelik, S. Y., Solak, K., & Mavi, A. (2019). Characterization of an interesting selenium-dependent glutathione peroxidase (Se-GPx) protecting cells against environmental stress: The Camelus dromedarius erythrocytes Se-GPx. Biocatalysis and Agricultural Biotechnology, 18, 101000.
  14. Cakmak, K., BAYRAM, Ö., SOLAK, K., KABAN, G., ŞİMŞEK, Ö., & Mavi, A. (2019). Plasma polymerized linalool (ppLin): an antimicrobial and biocompatible coating. Turkish Journal of Chemistry, 43(1), 323-334.
  15. Celik, H., Aydin, T., Solak, K., Khalid, S., & Farooqi, A. A. (2018). Curcumin on the “flying carpets” to modulate different signal transduction cascades in cancers: next‐generation approach to bridge translational gaps. Journal of cellular biochemistry, 119(6), 4293-4303.
  16. Chafik, A., Essamadi, A., Çelik, S. Y., Solak, K., & Mavi, A. (2018). Partial purification and some interesting properties of glutathione peroxidase from liver of camel (Camelus dromedarius). Russian Journal of Bioorganic Chemistry, 44(1), 41-51.
  17. Solak, K., Mavi, A., Ergon, T., Sezen, A., & Algur, Ö. F. (2017). Nanomaterials and the microbial sphere. Nanoscience and Nanotechnology Letters, 9(5), 609-623.