PI
Saltuk Buğrahan CEYHUN, PhD

I extend my infinite gratitude to God for zebrafish, His gracious gift to the world of science..

Projects Completed

0

We conduct research focused on disease
modeling
and toxicology

In our laboratory, we model diseases like obesity, anxiety, and depression to uncover their underlying mechanisms and explore alternative treatment approaches. Additionally, we examine the toxicity of various food additives, pesticides, and nano-sized plastics, aiming to assess their potential risks to human health.

Food additives
With an innovative approach, we explore the impact of food additives by precisely microinjecting them into the yolk sac (food) of zebrafish during the embryonic development stage.

Nanoplastics & Pesticides
We explore how widely used pesticides and nano-sized plastic particles in global agricultural practices affect aquatic ecosystems and health. Our research sheds light on their potential risks, paving the way for a safer and more sustainable environment.

Behavior
We utilize advanced behavioral test systems to model neurodegenerative diseases and explore innovative treatment approaches. Additionally, we examine the impact of xenobiotics on behavior using specially designed behavioral analysis techniques.

Opportunities
Beyond our laboratory’s specialized equipment, DAYTAM (East Anatolian High Tec Research Center)—just 100 meters away—provides cutting-edge technology for advanced, in-depth analyses, offering a significant advantage for research.

CeyhunLab’s team successfully completed 13 projects already and we always welcome to collaboration all over the world within our scope and feel free to contacting and informing us about your idea.

Done By CeyhunLab

Thermal Targeting of Human Breast Cancer Cells in a Zebrafish Xenograft Model Using Recombinant DNA

Transgenerational Toxicity of Modified Mycotoxins: A Zebrafish Model Approach

Investigation of the Effect of Chronic Fluoride Application on Anxiety-Like Behavior and Circadian Clock in Zebrafish

Determination of Cellular Interaction of Fluorescently Labeled Polystyrene Nanoplastic Particles in Zebrafish Brain and Possible Damage Mechanisms

Co-exposure effect of different colour of LED lights and increasing temperature on zebrafish larvae (Danio rerio): Immunohistochemical, metabolomics, molecular and behaviour approaches

Global warming and nanoplastic toxicity; small temperature increases can make gill and liver toxicity more dramatic, which affects fillet quality caused by polystyrene nanoplastics in the adult zebrafish model

Antioxidant/protective effects of carob pod (Ceratonia siliqua L.) water extract against deltamethrin-induced oxidative stress/toxicity in zebrafish larvae

The anxiolytic and circadian regulatory effect of agarwood water extract and its effects on the next generation; zebrafish modeling

Fluoride exposure causes behavioral, molecular and physiological changes in adult zebrafish (Danio rerio) and their offspring

Global warming and glyphosate toxicity (I): Adult zebrafish modelling with behavioural, immunohistochemical and metabolomic approaches

Global warming and glyphosate toxicity (II): Offspring zebrafish modelling with behavioral, morphological and immunohistochemical approaches

Nano-sized polystyrene plastic particles affect many cancer-related biological processes even in the next generations; zebrafish modeling

The synergic toxicity of temperature increases and nanopolystrene on zebrafish brain implies that global warming may worsen the current risk based on plastic debris

Effects of the food colorant carmoisine on zebrafish embryos at a wide range of concentrations

A versatile toxicity evaluation of ethyl carbamate (urethane) on zebrafish embryos: Morphological, physiological, histopathological, immunohistochemical, transcriptional and behavioral approaches

The potential effect mechanism of high‑fat and high-carbohydrate diet induced obesity on anxiety and offspring of zebrafish

Is sodium carboxymethyl cellulose (CMC) really completely innocent? It may be triggering obesity

An approach to evaluating the potential teratogenic and neurotoxic mechanism of BHA based on apoptosis induced by oxidative stress in zebrafish embryo (Danio rerio)

Polystyrene nanoplastics (20 nm) are able to bioaccumulate and cause oxidative DNA damages in the brain tissue of zebrafish embryo (Danio rerio)

Co-exposure effect of different colour of LED lights and increasing temperature on zebrafish larvae (Danio rerio): Immunohistochemical, metabolomics, molecular and behaviour approaches November 15, 2024

CeyhunLab is one of the select laboratories in our country approved by the Ministry, dedicated to contributing to global science through cutting-edge research on zebrafish using behavioral and molecular-based approaches.

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