{"id":536,"date":"2025-09-01T21:58:21","date_gmt":"2025-09-01T18:58:21","guid":{"rendered":"https:\/\/laboratuvar.atauni.edu.tr\/ceyhunlab\/?p=536"},"modified":"2025-10-07T22:30:23","modified_gmt":"2025-10-07T19:30:23","slug":"neurotoxic-effects-of-n-nitrosodimethylamine-ndma-in-zebrafish-intergenerational-transmission-with-transcriptomic-metabolomic-and-behavioral-analyses","status":"publish","type":"post","link":"https:\/\/laboratuvar.atauni.edu.tr\/ceyhunlab\/blog\/2025\/09\/01\/neurotoxic-effects-of-n-nitrosodimethylamine-ndma-in-zebrafish-intergenerational-transmission-with-transcriptomic-metabolomic-and-behavioral-analyses\/","title":{"rendered":"Neurotoxic Effects of N-Nitrosodimethylamine (NDMA) in Zebrafish: Intergenerational Transmission with Transcriptomic, Metabolomic, and Behavioral Analyses"},"content":{"rendered":"\n<figure class=\"wp-block-image size-large\"><img fetchpriority=\"high\" decoding=\"async\" width=\"1024\" height=\"418\" src=\"https:\/\/laboratuvar.atauni.edu.tr\/ceyhunlab\/wp-content\/uploads\/sites\/4\/2025\/10\/WhatsApp-Image-2025-10-07-at-20.28.26-1-1024x418.jpeg\" alt=\"\" class=\"wp-image-537\" srcset=\"https:\/\/laboratuvar.atauni.edu.tr\/ceyhunlab\/wp-content\/uploads\/sites\/4\/2025\/10\/WhatsApp-Image-2025-10-07-at-20.28.26-1-1024x418.jpeg 1024w, https:\/\/laboratuvar.atauni.edu.tr\/ceyhunlab\/wp-content\/uploads\/sites\/4\/2025\/10\/WhatsApp-Image-2025-10-07-at-20.28.26-1-300x122.jpeg 300w, https:\/\/laboratuvar.atauni.edu.tr\/ceyhunlab\/wp-content\/uploads\/sites\/4\/2025\/10\/WhatsApp-Image-2025-10-07-at-20.28.26-1-768x313.jpeg 768w, https:\/\/laboratuvar.atauni.edu.tr\/ceyhunlab\/wp-content\/uploads\/sites\/4\/2025\/10\/WhatsApp-Image-2025-10-07-at-20.28.26-1-1536x627.jpeg 1536w, https:\/\/laboratuvar.atauni.edu.tr\/ceyhunlab\/wp-content\/uploads\/sites\/4\/2025\/10\/WhatsApp-Image-2025-10-07-at-20.28.26-1.jpeg 1600w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>This project investigates how nitrosodimethylamine (NDMA), a potent environmental carcinogen, affects circadian rhythms and anxiety in zebrafish. Using behavioral tests, brain metabolomic and transcriptomic analyses, and dopamine\/serotonin measurements, the study examines both adult fish and their offspring to understand NDMA\u2019s intergenerational neurotoxic effects and potential health risks.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>This project investigates how nitrosodimethylamine (NDMA), a potent environmental carcinogen, affects circadian rhythms and anxiety in zebrafish. Using behavioral tests, brain metabolomic and transcriptomic analyses, and dopamine\/serotonin measurements, the study examines both adult fish and their offspring to understand NDMA\u2019s intergenerational neurotoxic effects and potential health risks.<\/p>\n","protected":false},"author":3,"featured_media":514,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5,13,7],"tags":[],"class_list":["post-536","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-active-project","category-all-projects","category-environmental"],"_links":{"self":[{"href":"https:\/\/laboratuvar.atauni.edu.tr\/ceyhunlab\/wp-json\/wp\/v2\/posts\/536","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/laboratuvar.atauni.edu.tr\/ceyhunlab\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/laboratuvar.atauni.edu.tr\/ceyhunlab\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/laboratuvar.atauni.edu.tr\/ceyhunlab\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/laboratuvar.atauni.edu.tr\/ceyhunlab\/wp-json\/wp\/v2\/comments?post=536"}],"version-history":[{"count":3,"href":"https:\/\/laboratuvar.atauni.edu.tr\/ceyhunlab\/wp-json\/wp\/v2\/posts\/536\/revisions"}],"predecessor-version":[{"id":543,"href":"https:\/\/laboratuvar.atauni.edu.tr\/ceyhunlab\/wp-json\/wp\/v2\/posts\/536\/revisions\/543"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/laboratuvar.atauni.edu.tr\/ceyhunlab\/wp-json\/wp\/v2\/media\/514"}],"wp:attachment":[{"href":"https:\/\/laboratuvar.atauni.edu.tr\/ceyhunlab\/wp-json\/wp\/v2\/media?parent=536"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/laboratuvar.atauni.edu.tr\/ceyhunlab\/wp-json\/wp\/v2\/categories?post=536"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/laboratuvar.atauni.edu.tr\/ceyhunlab\/wp-json\/wp\/v2\/tags?post=536"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}